Member Profile

Dr. H. Marijke van den Berg
MD, PhD

Dr. van den Berg attended the Faculty of Medicine, University of Groningen, The Netherlands. She received her degree as a medical doctor in 1980. She worked for 3 years in Internal medicine and Hematology. She defended her PhD thesis on Non Hodgkin Lymphomas in March1986.  She was trained as pediatrician and further specialized in Pediatric-Hematology/Oncology. She worked in The Free University Hospital for 5 years in Pediatric Hemato-Oncology. From 1991 until 2008 she worked in the University Hospital Utrecht as Director of the Van Creveldkliniek, Dutch National Center for Haemophilia and at the Department of Pediatric Hematology of the Wilhelmina Childrens Hospital.  She did a sabbatical with Prof Dr Gilbert White in Chapel Hill (USA) on the relation of HLA and inhibitor development. From 2008 until July 2011 she was CEO of a large teaching Hospital. Her expertise in Hemophilia is on inhibitors and prophylaxis. She has initiated as Principal investigator multicenter studies in inhibitors. From 2012 she hold a position as Associate Professor at the Department of Health Science and Epidemiology at the University Hospital of Utrecht, the Netherlands.

Key Publications
  1. Gouw SC, van der Bom JG, van den Berg HM. Treatment-related risk factors of inhibitor development in previously untreated patients with hemophilia A: the CANAL cohort study. Blood 2007;109:4648-54.
  2. van den Berg HM, Fischer K, Mauser-Bunschoten EP, Beek FJ, Roosendaal G, van der Bom JG, Nieuwenhuis HK. Long-term outcome of individualized prophylactic treatment of children with severe haemophilia. Br J Haematol 2001;112:561-5.
  3. Gouw SC, van der Bom JG, Auerswald G, Ettinghausen CE, Tedgård U, van den Berg HM. Recombinant versus plasma-derived factor VIII products and the development of inhibitors in previously untreated patients with severe hemophilia A: the CANAL cohort study. Blood 2007;109:4693-7.
  4. Fischer K, Astermark J, van der Bom JG, Ljung R, Berntorp E, Grobbee DE, van den Berg HM. Prophylactic treatment for severe haemophilia: comparison of an intermediate-dose to a high-dose regimen. Haemophilia 2002;8:753-60.
  5. van Dijk K, Fischer K, van der Bom JG, Grobbee DE, van den Berg HM. Variability in clinical phenotype of severe haemophilia: the role of the first joint bleed. Haemophilia 2005;11:438-43.

Current Positions/Chairs:

  • Pediatric Hematologist
  • Principal Investigator
    Principal Investigator of the Rodin study

Key Institutions

  • University Hospital of Utrecht
    Department of Health Science and Epidemiology
    the Netherlands

Research Interests

  • Inhibitors
  • Pharmacovigilance

Publications

January 28, 2011

Validation of a new pediatric joint scoring system from the International Hemophilia Prophylaxis Study Group: Validity of the Hemophilia Joint Health Score (HJHS).

Authors
Feldman BM, Funk S, Bergstrom B-M, Zourikian N, Hilliard P, van der Net J, Engelbert RHH, Petrini P, van den Berg M , Manco-Johnson M, Rivard GE, Abad A, and Blanchette VS.
Citation
Arthritis Care & Research 2011 Feb; 63 (2):223-30.
August 15, 2006

Reliability study of the Hemophilia Joint Health Score.

Authors
Hilliard P, Funk S, Zourikian N, Bergstrom B-M, Bradley CS, McLimont M, Manco-Johnson M, Petrini P, van den Berg M, and Feldman BM.
Citation
Haemophilia 2004 Oct; 10 (S3): 79 # 16 S 03.
August 15, 2006

Hemophilia joint health score reliability study.

Authors
Hilliard P, Funk S, Zourikian N, Bergstrom B-M, Bradley CS, McLimont M, Manco-Johnson M, Petrini P, van den Berg M, and Feldman BM.
Citation
Haemophilia 2006 Sept; 12: 518 – 525.
October 17, 2004

Reliability study of the Hemophilia Joint Health Score

The XXVI World Federation of Hemophillia Congress (October 17-21, 2004 - Bangkok, Thailand).
Authors
Hilliard P, Funk S, Zourikian N, Bergstrom B-M, Bradley CS, McLimont M, Manco-Johnson M, Petrini P, van den Berg M, and Feldman BM.
Citation
October 8, 2004

Physical therapy and imaging outcome measures in a haemophilia population treated with factor prophylaxis: current status and future directions.

Authors
Manco-Johnson MJ, Pettersson H, Petrini P, Babyn PS, Bergstrom B-M, Bradley CS , Doria AS, Feldman BM, Funk S, Hilliard P, Kilcoyne R, Lundin B, Nuss R, Rivard G, Schoenmakers MA, van den berg M, Wiedel J, Zourikian N, and Blanchette VS.
Citation
Haemophilia 2004 Oct; 10 (S4):88 – 93.